Twice-yearly shots used to treat AIDS were 100% effective in preventing new infections in women, according to study results published Wednesday.

There were no infections in the young women and girls that got the shots in a study of about 5,000 in South Africa and Uganda, researchers reported. In a group given daily prevention pills, roughly 2% ended up catching HIV from infected sex partners.

“To see this level of protection is stunning,” said Salim Abdool Karim of the injections. He is director of an AIDS research center in Durban, South Africa, who was not part of the research.

The results in women were published Wednesday in the New England Journal of Medicine and discussed at an AIDS conference in Munich. Gilead paid for the study and some of the researchers are company employees. Because of the surprisingly encouraging results, the study was stopped early and all participants were offered the shots, also known as lenacapavir.

      • Nurse_Robot@lemmy.world
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        4 months ago

        Yeah, I’m getting jaded as I get older. The optimist in me recognizes how ground breaking this is, and thinks there’s a real possibility of actually eradicating AIDS. The pessimist in me remembers covid.

    • Yawweee877h444@lemmy.world
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      4 months ago

      If there’s profit to be made treating HIV/AIDS symptoms without curing, the profit motive health industry won’t like this. Solve the problem, their profits go away.

        • Yawweee877h444@lemmy.world
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          4 months ago

          We can speculate very easily.

          There’s a trade-off, cost-benefit analysys. If a disease is so catastrophic that it kills everyone fast, well you’re not gonna make profit off them ever, because they die. Cure this one.

          What about diseases that can be controlled somewhat, and only affect small amounts of the population? What if for them to stay alive they have to stay on a regular concoction of expensive pharmaceuticals either forever or for a long time? And they can still go to work? Why cure this, out of altruism? That’s not how capitalism works.

          Let’s just say, for shits and giggles, we could cure immediately the common cold and mild influenza, forever. No more cough and cold over the counter medicine needed, much less pain and fever reducers. Local pharmacies don’t need to stock this stuff anymore. The companies that produce and sell these are all tied to wallstreet. Getting colds doesn’t stop you from working (or buying/consuming). Shit, I work with “men” who are “tough” who never call out of work sick because “I’m not a pussy” (cultural hardwork ethic propaganda nonsense).

          Etc., etc. You get my point.

          • thetreesaysbark@sh.itjust.works
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            4 months ago

            I’m not sure why you’re being downvoted.

            Correct me if I’m wrong but you’re not saying this is a good thing. Just that it is a thing.

            Makes sense to me. But I concede that I’m ignorant of what diseases we have cured recently, and too tired to research it right now.

            • KevonLooney@lemm.ee
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              4 months ago

              Yellow fever, cholera, mumps, polio, measles, and malaria were endemic in the US prior to their eradication. By “endemic” I mean children got them as often as chicken pox. They were almost unavoidable and killed millions.

              Measles and mumps are making a comeback due to anti-vax losers, but the others are still gone.

            • Yawweee877h444@lemmy.world
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              4 months ago

              The downvotes are meh, I’ve made similar comments that got more upvoted. Lemmy is a fickle beast and probably depends on the crowd at the time and their mood or the article or whatever.

              You’re correct, I was not saying this is good by any means. I want the profit motive removed from everything healthcare related. I was just giving an exaggerated simple example of how the capitalist profit motive could (and arguably does) work in some instances.

      • sznowicki@lemmy.world
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        4 months ago

        Then some other company will do it. Not all world is US and A. Is some areas like Europe the states would be more than happy to order those vaccines to treat their citizens. There’s demand made by public health organizations, there will be someone willing to join the race and eat that cake.

      • iorale@lemmy.dbzer0.com
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        4 months ago

        Why would they? There are other STD and this vaccine doesn’t cover those nor prevents pregnancy.
        … Oh right, people are idiots and will think this is some sort of panacea…

        Still, hope my country politicians won’t refuse this one like they keep refusing the one for covid or the ones for the newborns.

        • Diplomjodler@lemmy.world
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          4 months ago

          AIDS has been the most dangerous STD for decades. It has changed attitudes to sex worldwide. Having a vaccine is going to change them again.

          • iorale@lemmy.dbzer0.com
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            4 months ago

            You missed my point tho, this vaccine will be a must for everyone and extremely helpful, but it won’t protect people from the rest of the STD nor pregnancy, this means people would still need to wear a condom but I firmly believe most people will just go and say «I already got my shot» and completely disregard the condom.

            • Diplomjodler@lemmy.world
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              4 months ago

              Most other STDs are curable with antibiotics. And there’s contraceptives. AIDS was always something different, even after it was treatable.

              • iorale@lemmy.dbzer0.com
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                4 months ago

                Cool, still missing my point (either maliciously or not).

                Lemme spell it out, idiots are going to try to disregard the use of condoms using the vaccine as an excuse. It doesn’t matter if other STD can be cured, it’s always best to not get infected at all; if someone isn’t ready to have a kid, they still have to wear a condom.

                Wear a condom anyway, unless actively trying for a kid.

          • sandbox@lemmy.world
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            4 months ago

            There’s already very effective medicine available in the west to treat and prevent HIV/AIDS, we call it PrEP.

            • KevonLooney@lemm.ee
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              4 months ago

              This is more effective than prep and easier, because you only need a shot every 6 months. The testing for this new shit involved using prep for the control group.

              The new medicine worked so well they stopped the trial and gave the control group the shot. No one with the shot got sick at all. If they had continued with the control group, a few of them would have gotten AIDS.

        • nutt_goblin@lemmy.world
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          4 months ago

          Not to sell out my community but I know quite a few people whose condom use went down after they got on PrEP

  • ShadowRam@fedia.io
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    4 months ago

    twice-yearly

    I wonder why they went with that, instead of saying bi-annually